Immunity and Cancer
Role in Immunity: Vitamin D is known to activate the innate immune system of the body. Deficiency is known to make individuals susceptible to viral infections, sometimes as severe as HIV. In ancient times, Vitamin D was administered to treat tuberculosis. It was found that the intake of this vitamin may also control the severity of respiratory infections. Preliminary evidence suggests that a deficiency of Vitamin D may be one of the reasons for making individuals more sensitive to respiratory infections in the on-going pandemic, COVID-19, though its exact role is not clearly known in the treatment or prevention of the actual condition. Improvement is seen in individuals suffering from Ulcerative colitis and Crohn’s disease when administered with Vitamin D. An effective inflammatory response also needs this vitamin.
Role in Cancer: Vitamin D and its supplements are known to exhibit anti-cancer properties. Studies suggest its role in cell differentiation and stimulation of apoptosis apart from inhibition of the growth of cancerous cells. It is also involved in the reduction of angiogenesis, by which the blood supply to the cancer cells is decreased, retarding their growth. Pancreatic, colo-rectal, breast, and prostate cancer were studied in relation to levels of Vitamin D to analyze whether or not it plays any role in cancer prevention and treatment. Numerous studies indicated that optimal levels of Vitamin D reduced the risk of colo-rectal cancer.
Cardiovascular Diseases and Other Functions:
Role in Cardiovascular diseases: Low levels of Vitamin D are associated with a higher risk of cardiovascular diseases, like heart failure and hypertension. So, supplementation may reduce the risk of these diseases. It is also known to lower blood pressure and improve glycemic control.
Other Functions:
A study carried out by researchers of Kyoto University showed that Vitamin D regulates levels of lipids by inhibiting the protein involved in lipid production.
In the elderly, the intake of Vitamin D supposedly decreased the risk of mortality. This research is preliminary and needs to be further investigated.
It relieves symptoms of depression to a certain extent.
Vitamin D is known to play a role in controlling cognitive impairment and reduces the risk of diseases like Alzheimer’s.
In pregnant women, the maintenance of Vitamin D levels is known to prevent pre-eclampsia. It also reduces the risk of gestational diabetes.
Some studies, though they are not conclusive, also suggest the role of Vitamin D in weight loss when coupled with the restriction of calories.
Due to its role in the absorption of calcium, it also helps in the maintenance of healthy teeth.
It maintains healthy lungs due to its anti-inflammatory properties.
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