Hyperinsulinemia is a medical condition resulting when the body contains an excess amount of insulin. It may be associated with insulin resistance and diabetes. One of the chief causes of hyperinsulinemia is believed to be insulin resistance where the cells cannot use insulin efficiently. As the blood glucose levels continue to rise due to insulin resistance, the pancreas continues to produce more and more insulin to tackle the glucose levels. Over time, the pancreas cannot keep up with the demand, ultimately leading to type 2 diabetes. Other clinical conditions such as Insulinoma (a type of tumor) and nesidioblastosis (excess cells that produce insulin) may also lead to hyperinsulinemia. Hyperinsulinemia is referred to as â€˜silent diseaseâ€™, as no symptoms are observed. Primary treatment involves lifestyle changes such as diet, exercise, and weight loss. Diet plays a vital role in tackling this condition. Foods having a low glycemic index and low carbohydrates are beneficial. If these options are not satisfactory, drugs used in diabetes treatment may be employed.
Insulinoma is a tumor in the pancreas. Beta cells of the pancreas that are involved in the production of insulin become tumorous. On contrary to producing more insulin in conditions of high blood sugar, this condition results in the continuous production of insulin. they show symptoms of low blood sugar such as sweating, weakness, confusion, dizziness, headache, blurred vision, lethargy, fast heartbeat, etc. Women and individuals in the age group 40 to 60 are most likely to be diagnosed with insulinoma. Certain genetic conditions such as neurofibromatosis type 1, tuberous sclerosis, and multiple endocrine neoplasia type-1 also increase the susceptibility of insulinoma. Diagnosis is by carrying out blood tests and suppression tests such as blood sugar, insulin, c-peptide, etc. Imaging tests such as CT scans, ultrasound, and MRI may also be carried out to detect the tumor. The main treatment option is the removal of the tumor. These tumors arenâ€™t cancerous always and can be surgically removed. The size, type, and location of the tumor decide the type of surgery that needs to be undertaken. The tumor may also be removed by laparoscopy. In rare cases, where the tumor is cancerous, chemotherapy and radiotherapy will be needed.
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